Summary: The deregulation of the actin cytoskeleton has been extensively studied in metastatic dissemination.However, the post-dissemination role of the actin cytoskeleton dysregulation is poorly understood.Here, we report that fascin, an actin-bundling protein, promotes lung cancer metastatic colonization by augmenting metabolic stress resistance
The work aims to study the root mean square (RMS) responses to acceleration input for four state variables: the ms vertical acceleration, the ms pitch angular acceleration and the front and rear deflections of the suspensions.A half-car two degree-of-freedom model of semi-active control scheme is analyzed and compared with the Refurbished Espresso
Abstract.Background.Sepsis is the leading cause of death in hospitalized patients and significant effort has been made to facilitate early diagnosis and management.However, aggressive treatment can have negative effects, especially in patients with unstable volume status, such as those with congestive heart failure.Methods.We used electronic medica
Representation learning has proven to be a powerful methodology in a wide variety of machine-learning applications.For atmospheric dynamics, however, it has so far not been considered, arguably due to the lack of large-scale, labeled datasets that could be used for training.In this work, we show how to sidestep the difficulty and introduce a self-s
The article discusses several epistemological and methodological issues related to the analysis of discourse in general and of educational talk in particular.The avocado slicer theoretical framework provided by conversation analysis (CA) is applied and critically discussed in the analysis of an empirical example of educational talk.Several question